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5-碘水杨酸

5-碘水杨酸用途

【用途一】
用作医药中间体

5-碘水杨酸名称

[ CAS 号 ]:
119-30-2

[ 中文名 ]:
5-碘水杨酸

[ 英文名 ]:
5-Iodosalicylic acid

[中文别名 ]:

[英文别名 ]:

EINECS 204-313-5
5-Iodosalicylic acid
Benzoic acid, 2-hydroxy-5-iodo-
2-Hydroxy-5-iodobenzoic acid
MFCD00002458

5-碘水杨酸物理化学性质

[ 密度 ]:
2.2±0.1 g/cm3

[ 沸点 ]:
371.4±37.0 °C at 760 mmHg

[ 熔点 ]:
189-191 °C(lit.)

[ 分子式 ]:
C₇H₅IO₃

[ 分子量 ]:
264.017

[ 闪点 ]:
178.4±26.5 °C

[ 精确质量 ]:
263.928314

[ PSA ]:
57.53000

[ LogP ]:
3.67

[ 外观性状 ]:
略米色粉末

[ 蒸汽压 ]:
0.0±0.9 mmHg at 25°C

[ 折射率 ]:
1.712

[ 储存条件 ]:
室温，干燥

5-碘水杨酸MSDS

5-碘水杨酸毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VO4200000

CHEMICAL NAME :: Salicylic acid, 5-iodo-

CAS REGISTRY NUMBER :: 119-30-2

BEILSTEIN REFERENCE NO. :: 2090443

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C7-H5-I-O3

MOLECULAR WEIGHT :: 264.02

WISWESSER LINE NOTATION :: QVR BQ EI

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold

REFERENCE :: CBCCT* "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. (National Academy of Science Library, 2101 Constitution Ave., NW, Washington, DC 20418) Volume(issue)/page/year: 5,341,1953

5-碘水杨酸安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi:Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S37/39

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
VO4200000

[ 海关编码 ]:
29182990

5-碘水杨酸合成路线

5-碘水杨酸上下游产品

5-碘水杨酸上游产品

5-碘水杨酸下游产品

5-碘水杨酸海关

[ 海关编码 ]: 2918290000

[ 中文概述 ]:
2918290000 其他含酚基但不含其他含氧基羧酸及其酸酐、酰卤化物、过氧化物和过氧酸及它们的衍生物。监管条件:AB(入境货物通关单,出境货物通关单)。增值税率:17.0%。退税率:9.0%。最惠国关税:6.5%。普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ 监管条件 ]: A.入境货物通关单 B.出境货物通关单

[ 检验检疫 ]: R.进口食品卫生监督检验 S.出口食品卫生监督检验

[ Summary ]:
HS: 2918290000 other carboxylic acids with phenol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) VAT:17.0% MFN tariff:6.5% General tariff:30.0%

5-碘水杨酸文献

Iodination of salicylic acid improves its binding to transthyretin.

Biochim. Biophys. Acta 1784(3) , 512-7, (2008)

Transthyretin (TTR) is a plasma homotetrameric protein associated with senile systemic amyloidosis and familial amyloidotic polyneuropathy. In theses cases, TTR dissociation and misfolding induces the...

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