| 常用名 | RTI-7470-44 | CAS号 | 825658-63-7 |
|---|---|---|---|
| 价格 | ¥1.0/1g ¥1.0/5g | 纯度 | 98.0% |
| 备货期 | 2天 | 库存 | 询单 |
| 产品详情(用途,包装等)
用途: RTI-7470-44 is a potent, selective human trace amine-associated receptor subtype 1 (hTAAR1) antagonist with IC50 of 8.4 nM in vitro cAMP functional assay.RTI-7470-44 exhibits a Ki of 0.3 nM in a radioligand binding assay, and shows species selectivity (>90-fold) for hTAAR1 over the rat and mouse orthologues.RTI-7470-44 displays good blood–brain barrier permeability, moderate metabolic stability, and a favorable preliminary off-target profile.RTI-7470-44 increased the spontaneous firing rate of mouse VTA dopaminergic neurons and blocked the effects of the known TAAR1 agonist RO5166017. 物理化学性质: CAS号:825658-63-7 常用中文名:RTI-7470-44 常用英文名:RTI-7470-44 分子式:C19H11ClF3N5Os 分子量:449.836 密度:N/A 沸点:N/A 熔点:N/A 闪点:N/A |