常用名 | DQP-997-74 | CAS号 | 2377187-09-0 |
---|---|---|---|
价格 | ¥需询单/100mg ¥需询单/250mg ¥需询单/1g ¥220.0/10ml | 纯度 | 98.0% |
备货期 | 10天 | 库存 | 3 |
产品详情(用途,包装等)
用途: DQP-997-74 (compound 2i) is a selective inhibitor of N-methyl-d-aspartate receptor (NMDAR), specifically targeting GluN2C/D (IC50: 0.069 μM and 0.035 μM), with Blood-brain permeability. Where DQP refers to dihydroquinoline-pyrazoline. DQP-997-74 acts synergistically with the agonist glutamate to exhibit time-dependent enhanced potency in inhibiting hypersynchronous activity driven by high-frequency excitatory synaptic transmission. DQP-997-74 reduces the number of epileptogenesis in a murine model of tuberous sclerosis complex (TSC)-induced epilepsy. DQP-997-74 can be used for research on NMDAR-related neurological diseases[1]. 物理化学性质: CAS号:2377187-09-0 常用中文名:DQP-997-74 常用英文名:DQP-997-74 分子式:C28H19Cl2F2N3O4 分子量:570.37 密度:N/A 沸点:N/A 熔点:N/A 闪点:N/A |