(E)-3-(4-((1H-咪唑-1-基)甲基)苯基)丙烯酸
更新时间：2025-08-24 09:20:20
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| 常用名 | 奥扎格雷 | CAS号 | 82571-53-7 |
|---|---|---|---|
| 价格 | 纯度 | 98.0% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情（用途，包装等）
用途： Ozagrel(OKY-046) is an antiplatelet agent working as a thromboxane A2 synthesis inhibitor.Target: Thromboxane A2 SynthaseOzagrel was selected as the best compound of highly selective inhibitors of TXA2 synthase. The inhibition of TXA2 synthase by ozagrel was more effective on human and rabbit enzymes than those of other species. Ozagrel increased 6-keto-PGF1 alpha, one of stable metabolites of PGI2, in various isolated cells and tissues perhaps via accumulated PG endoperoxides resulted by the inhibition of TXA2 synthase [1]. Ozagrel was estimated to be a reversible mixed-type inhibitor of diphenolase activity with the constants (K (S1), K (S2), K (i1), and K (i2)) determined to be 2.21, 3.89, 0.454, and 0.799 mM, repectively [2]. Infusion of OKY-046 significantly inhibited pulmonary thromboxane B2 delivery, attenuated the early increase in pulmonary vascular resistance, and blocked the increase in systemic vascular resistance. In addition, OKY-046 blunted and delayed the decrease in cardiac output and maintained end-systolic pressure-diameter relation, +dp/dt, and lung lymph flow at baseline values [3]. 物理化学性质： CAS号：82571-53-7 常用中文名：奥扎格雷 常用英文名：Ozagrel 分子式：C13H12N2O2 分子量：228.247 密度：1.2±0.1 g/cm3 沸点：468.0±25.0 °C at 760 mmHg 熔点：223 - 224ºC 闪点：236.8±23.2 °C 储存条件：存放于惰性气体之中;避免空气 |
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- 产品名：(E)-3-(4-((1H-咪唑-1-基)甲基)苯基)丙烯酸
- 价格：
- 纯度：98.0%
- 备货期：10天
- 联系人：徐经理
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参考价格：$66/10mM*1mLinDMSO