盐酸多沙普仑
更新时间：2025-08-27 09:51:34
采购访问：32次
| 常用名 | 盐酸多沙普仑 | CAS号 | 7081-53-0 |
|---|---|---|---|
| 价格 | 纯度 | 98.0% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情（用途，包装等）
用途： Doxapram hydrochloride hydrate inhibits TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel function with EC50 of 410 nM, 37 μM, 9 μM, respectively.Target: Potassium ChannelDoxapram is a respiratory stimulant. Doxapram (15-150 microM) also evoked 3H overflow in a concentration dependent manner, and doxapram-evoked release was inhibited by the Ca2+ channel blocker nifedipine (5 microM). Analysis of released tritiated compounds suggested that doxapram preferentially stimulated the release of dopamine. Our results indicate that the mechanism of action of doxapram shares similarities with that of hypoxia in the carotid body [1]. Doxapram (1-100 microM) caused rapid, reversible and dose-dependent inhibitions of K+ currents recorded in type I cells (IC50 approximately 13 microM). doxapram was also seen to directly inhibit Ca(2+)-independent K+ currents. Doxapram was a more potent inhibitor of the Ca(2+)-activated K+ currents recorded under control conditions. Doxapram (10 microM) was without effect on L-type Ca2+ channel currents recorded under conditions where K+ channel activity was minimized and was also without significant effect on K+ currents recorded in the neuronal cell line NG-108 15, suggesting a selective effect on carotid body type I cells. The effects of doxapram on type I cells show similarities to those of the physiological stimuli of the carotid body, suggesting that doxapram may share a similar mechanism of action in stimulating the intact organ [2]. 物理化学性质： CAS号：7081-53-0 常用中文名：盐酸多沙普仑 常用英文名：Doxapram (hydrochloride hydrate) 分子式：C24H33ClN2O3 分子量：432.983 密度：N/A 沸点：N/A 熔点：217-219° 闪点：N/A 储存条件：室温，干燥 |
上海化源世纪贸易有限公司
认证状态：已认证供应商
商品数：396716件
电话：53555033
地址：上海市普陀区金沙江路1759号圣诺亚大厦B座
地区： 上海市 上海市 普陀区
联系人：徐经理
联系人电话：13311869306
邮件：xuqm@chemsrc.com
网址：http://www.chemsrc.com
主要市场：
年贸易额：
外贸占销售比例：
主要合作伙伴：
- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：盐酸多沙普仑一水合物
- 价格： ￥799.9/100mg ￥319.9/25mg ￥723.9/1ml ￥2799.9/500mg
- 纯度：98.0%
- 备货期：1天
- 联系人：阿拉丁
- 上海化源世纪贸易有限公司
- 上海市 上海市 普陀区
- 产品名：盐酸多沙普仑
- 价格：
- 纯度：98.0%
- 备货期：10天
- 联系人：徐经理
- 上海阿摩尔生物科技有限公司
- 上海市 上海市 奉贤区
- 产品名：盐酸多沙普仑一水合物
- 价格： ￥需询单/100mg ￥需询单/10mg ￥需询单/1g ￥需询单/250mg
- 纯度：98.0%
- 备货期：需询单
- 联系人：王汐瑶
查看所有供应商和价格请点击：
参考价格：$106/10mM*1mLinDMSO