盐酸多沙普仑结构式
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常用名 | 盐酸多沙普仑 | 英文名 | Doxapram (hydrochloride hydrate) |
|---|---|---|---|---|
| CAS号 | 7081-53-0 | 分子量 | 432.983 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C24H33ClN2O3 | 熔点 | 217-219° | |
| MSDS | N/A | 闪点 | N/A | |
| 符号 |
GHS06 |
信号词 | Danger |
盐酸多沙普仑用途Doxapram能抑制TASK-1，TASK-3和TASK-1/TASK-3异二聚体通道，EC50分别为410 nM，37 μM和9 μM。 |
| 中文名 | 盐酸多沙普仑 |
|---|---|
| 英文名 | doxapram hydrochloride monohydrate |
| 中文别名 | 1-乙基-3,3-二苯基-4-[2-(4-吗啉基)乙基]-2-吡咯烷酮盐酸盐一水合物 | 香草醛.香兰素 |
| 英文别名 | 更多 |
| 描述 | Doxapram能抑制TASK-1,TASK-3和TASK-1/TASK-3异二聚体通道,EC50分别为410 nM,37 μM和9 μM。 |
|---|---|
| 相关类别 | |
| 参考文献 |
| 熔点 | 217-219° |
|---|---|
| 分子式 | C24H33ClN2O3 |
| 分子量 | 432.983 |
| 精确质量 | 432.217957 |
| PSA | 42.01000 |
| LogP | 3.78680 |
| 储存条件 | 室温，干燥 |
| 水溶解性 | Soluble in water, in alcohol and in methylene chloride. |
| 符号 |
GHS06 |
|---|---|
| 信号词 | Danger |
| 危害声明 | H301 |
| 警示性声明 | Missing Phrase - N15.00950417 |
| 危险品运输编码 | UN 2811 6.1 / PGIII |
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Doxapram and hypokalaemia in very preterm infants.
Arch. Dis. Child Fetal Neonatal Ed. 98(5) , F416-8, (2013) We observed two preterm infants who developed severe hypokalaemia following doxapram. We therefore wished to review the possible association between doxapram and severe hypokalaemia.A retrospective st... |
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Respiratory inductive plethysmography as a method for measuring ventilatory parameters in conscious, non-restrained dogs.
J. Pharmacol. Toxicol. Methods 62(1) , 47-53, (2010) Assessing the effects of new chemical entities on respiratory function in animal models is an essential component of preclinical drug safety evaluation. Methods currently available for measuring venti... |
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Acid-sensitive channel inhibition prevents fetal alcohol spectrum disorders cerebellar Purkinje cell loss.
Am. J. Physiol. Regul. Integr. Comp. Physiol. 295(2) , R596-603, (2008) Ethanol is now considered the most common human teratogen. Educational campaigns have not reduced the incidence of ethanol-mediated teratogenesis, leading to a growing interest in the development of t... |
| 1-Ethyl-4-(2-morpholinoethyl)-3,3-diphenyl-2-pyrrolidinone monohydrochloride monohydrate |
| UNII:P5RU6UOQ5Y |
| Doxapram hydrochloride monohydrate |
| Dopram |
| Doxapram HCL |
| Stimulexin |
| Doxapram monohydrochloride monohydrate |
| AHR 619 |
| Doxapram Hydrochloride hydrate |
| 1-Ethyl-4-[2-(4-morpholinyl)ethyl]-3,3-diphenyl-2-pyrrolidinone hydrochloride hydrate |
| Dopram (TN) |
| 2-Pyrrolidinone, 1-ethyl-4-[2-(4-morpholinyl)ethyl]-3,3-diphenyl-, hydrochloride, hydrate (1:1:1) |
| 1-Ethyl-4-[2-(morpholin-4-yl)ethyl]-3,3-diphenylpyrrolidin-2-one hydrochloride hydrate |
| Doxapram Hydrochloride |
| 1-ethyl-4-(2-morpholin-4-ylethyl)-3,3-diphenylpyrrolidin-2-one,hydrate,hydrochloride |
| 1-Ethyl-4-(2-morpholinoethyl)-3,3-diphenyl-2-pyrrolidinone hydrochloride hydrate |
| Doxapram HCl H2O |
| Doxapram (hydrochloride hydrate) |
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