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非尔氨酯

更新时间:2025-09-01 12:04:37 采购访问:58次

常用名 非氨酯 CAS号 25451-15-4
价格 纯度 99.0%
备货期 10天 库存 现货
 产品详情(用途,包装等)
用途:
Felbamate (FBM) is a potent nonsedative anticonvulsant whose clinical effect may be related to the inhibition of N-methyl-D-aspartate (NMDA) .Target: NMDA ReceptorFelbamate (marketed under the brand name Felbatol by MedPointe) is an anti-epileptic drug used in the treatment of epilepsy. It is used to treat partial seizures (with and without generalization) in adults and partial and generalized seizures associated with Lennox-Gastaut syndrome in children. However, an increased risk of potentially fatal aplastic anemia and/or liver failure limit the drugs usage to severe refractory epilepsy.Felbamate has been proposed to a unique dual mechanism of action as a positive modulator of GABAA receptors and as a blocker of NMDA receptors, particularly isoforms containing the NR2B subunit. Although it is clear that felbamate does cause pharmacological inhibition of NMDA receptor of relevance of NMDA receptor blockade as a strategy for the treatment of human epilepsy has been questioned. Therefore, the importance of the effects of felbamate on NMDA receptors to its therapeutic action in epilepsy is uncertain.
物理化学性质:
CAS号:25451-15-4
常用中文名:非氨酯
常用英文名:felbamate
分子式:C11H14N2O4
分子量:238.240
密度:1.3±0.1 g/cm3
沸点:511.9±50.0 °C at 760 mmHg
熔点:148-1500C
闪点:288.4±26.4 °C
储存条件:Store at RT

供应商信息

上海化源世纪贸易有限公司 认证供应商

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参考价格:$66/10mM*1mLinDMSO
其他供应商价格:
2022-02-19 非氨酯
价格:¥310.9
2022-05-12 Felbamate
价格:$需询单
2021-02-06 Felbamate
价格:¥889.0

查看所有价格,请点击非氨酯价格