| 常用名 | 托卡朋 | CAS号 | 134308-13-7 |
|---|---|---|---|
| 价格 | 纯度 | 99.0% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: Tolcapone(Ro 40-7592) is an orally active selective, potent catechol-O-methyltransferase (COMT) inhibitor. IC50 value:Target: COMTTolcapone inhibits both central and peripheral COMT. Tolcapone caused a rapid and reversible inhibition of COMT activity in erythrocytes in parallel with a dose-dependent decrease in the formation of 3-OMD. Tolcapone increased the area under the concentration-time curve and elimination half-life of levodopa. Tolcapone crosses the blood-brain barrier, and has been used for L-DOPA adjunct therapy in the treatment of Parkinson's disease. 物理化学性质: CAS号:134308-13-7 常用中文名:托卡朋 常用英文名:Tolcapone 分子式:C14H11NO5 分子量:273.241 密度:1.4±0.1 g/cm3 沸点:485.6±45.0 °C at 760 mmHg 熔点:126-128ºC 闪点:205.7±17.2 °C 储存条件:-20°C Freezer |