| 常用名 | NB-360 | CAS号 | 1262857-73-7 |
|---|---|---|---|
| 价格 | 纯度 | 99.25% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: NB-360 is a potent, brain penetrable, and orally bioavailable dual BACE1/BACE2 inhibitor (IC50: mouse and human BACE1=5 nM; BACE2=6 nM). NB-360 shows a superior pharmacological profile and robust reduction of amyloid-β and neuroinflammation in amyloid precursor protein(APP) transgenic mice. NB-360 can completely block the progression of Aβ deposition in the brains of APP transgenic mice. NB-360 shows excellent selectivity over the related aspartyl proteases pepsin, cathepsin D and cathepsin E[1][2]. 物理化学性质: CAS号:1262857-73-7 常用中文名:NB-360 常用英文名:NB-360 分子式:C21H19F4N5O2 分子量:449.40 密度:N/A 沸点:N/A 熔点:N/A 闪点:N/A |