| 常用名 | Crebinostat | CAS号 | 1092061-61-4 |
|---|---|---|---|
| 价格 | 纯度 | 98.0% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: Crebinostat is a potent histone deacetylase (HDAC) inhibitor with IC50 values of 0.7 nM, 1.0 nM, 2.0 nM and 9.3 nM for HDAC1, HDAC2, HDAC3 and HDAC6, respectively. Crebinostat potently induces acetylation of both histone H3 and histone H4 as well as enhances the expression of the cAMP response element-binding protein (CREB) target gene Egr1. Crebinostat increases the density of synapsin-1 punctae along dendrites in cultured neurons. Crebinostat can modulate chromatin-mediated neuroplasticity and exhibits enhanced memory in mice[1]. 物理化学性质: CAS号:1092061-61-4 常用中文名:Crebinostat 常用英文名:Crebinostat 分子式:C20H23N3O3 分子量:353.415 密度:1.2±0.1 g/cm3 沸点:N/A 熔点:N/A 闪点:N/A |