| 常用名 | 氧氟沙星 | CAS号 | 82419-36-1 |
|---|---|---|---|
| 价格 | ¥需询单/1g | 纯度 | 98.0% |
| 备货期 | 1天 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: Ofloxacin is a fluoroquinolone whose primary mechanism of action is inhibition of bacterial DNA gyrase.Target: DNA gyrase Ofloxacin is a fluoroquinolone whose primary mechanism of action is inhibition of bacterial DNA gyrase. In vitro it has a broad spectrum of activity against aerobic Gram-negative and Gram-positive bacteria, although it is poorly active against anaerobes [1]. Ofloxacin, like other 4-quinolones, is unusual among front line drugs available to treat bacterial infections since it affects bacterial DNA synthesis, rather than cell wall or protein synthesis [2].Ofloxacin (20 mg/kg), norfloxacin (40 mg/kg), pefloxacin mesylate dihydrate (40 mg/kg)and ciprofloxacin (50 mg/kg) were administered by gavage twice daily for three consecutive weeks. 6 weeks after treatment, the test animals were euthanised and Achilles tendon specimens were collected. A computer monitored tensile testing machine was utilised for biomechanical testing. The mean elastic modulus of the control group was significantly higher than that of the norfloxacin and pefloxacin groups (p 物理化学性质: CAS号:82419-36-1 常用中文名:氧氟沙星 常用英文名:Ofloxacin 分子式:C18H20FN3O4 分子量:361.367 密度:1.5±0.1 g/cm3 沸点:571.5±50.0 °C at 760 mmHg 熔点:270-2750C 闪点:299.4±30.1 °C 储存条件:2-8°C |