| 常用名 | Larixol | CAS号 | 1438-66-0 |
|---|---|---|---|
| 价格 | ¥2031.0/5mg ¥需询单/1g ¥需询单/1g ¥需询单/1g | 纯度 | 98.0% |
| 备货期 | 1天 | 库存 | 现货 |
| 产品网页 | http://www.aladdin-e.com/zh_cn/L354287.html | ||
| 产品详情(用途,包装等)
用途: Larixol is an fMLP inhibitor and also inhibits Src kinase, ERK1/2, p38 and AKT phosphorylation signals in immune regulation. Larixol can interfere with the interaction between the βγ subunit of the fMLP receptor Gi protein and its downstream molecules, thereby inhibiting fMLP-induced respiratory burst. Larixol inhibits fMLP (0.1 μM)-induced superoxide anion production (IC50: 1.98 μM), cathepsin G release (IC50: 2.76 μM), and chemotaxis. Larixol improves neutrophil hyperactivation and reduces inflammation or tissue damage. A series of Larixol derivatives were found to have inhibitory effects on FSGS-related TRPC6 functional mutants[1][2]. 物理化学性质: CAS号:1438-66-0 常用中文名:Larixol 常用英文名:Larixol 分子式:C24H38O4 分子量:390.55600 密度:1.01g/cm3 沸点:440.5ºC at 760mmHg 熔点:N/A 闪点:205.3ºC |