MDL72274
更新时间：2024-07-17 15:06:48
采购访问：30次
| 常用名 | MDL72274 HCl | CAS号 | 85278-24-6 |
|---|---|---|---|
| 价格 | $需询单/100mg $需询单/250mg $需询单/500mg | 纯度 | 98.0% |
| 备货期 | 3天 | 库存 | 3 |
| 产品网页 | https://www.dcchemicals.com/product_show-MDL72274.html | ||
| 产品详情（用途，包装等）
MDL-72274 HCl is selective and potent inhibitors of SSAO for treatment of Parkinson diseases. MDL-72974 is a potent (IC50 = 10(-9) M) inhibitor of both MAO-B and SSAO, with 190-fold lower affinity for MAO-A. In clinical studies, oral doses as low as 100 micrograms produced substantial inhibition of platelet MAO-B. One or 4 mg MDL-72274 HCl given daily for 28 days to 40 Parkinson's patients treated with L-dopa produced statistically significant reductions in the Unified Parkinson's Disease Rating Scale. MAO-B inhibitors, such as MDL 72974A and L-deprenyl, offer the potential of being neuroprotective in Parkinson's Disease and other neurogenerative disorders. |
DC Chemicals Limited
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