| 常用名 | MDL72274 HCl | CAS号 | 85278-24-6 |
|---|---|---|---|
| 价格 | ¥需询单/100mg ¥需询单/500mg ¥需询单/1g ¥需询单/10g | 纯度 | 98.0% |
| 备货期 | 需询单 | 库存 | 询单 |
| 产品详情(用途,包装等)
用途: MDL-72274 HCl is selective and potent inhibitors of SSAO for treatment of Parkinson diseases. MDL-72974 is a potent (IC50 = 10(-9) M) inhibitor of both MAO-B and SSAO, with 190-fold lower affinity for MAO-A. In clinical studies, oral doses as low as 100 micrograms produced substantial inhibition of platelet MAO-B. One or 4 mg MDL-72274 HCl given daily for 28 days to 40 Parkinson's patients treated with L-dopa produced statistically significant reductions in the Unified Parkinson's Disease Rating Scale. MAO-B inhibitors, such as MDL 72974A and L-deprenyl, offer the potential of being neuroprotective in Parkinson's Disease and other neurogenerative disorders. 物理化学性质: CAS号:85278-24-6 常用中文名:MDL72274 HCl 常用英文名:MDL72274 HCl 分子式:C9H11Cl2N 分子量:204.09600 密度:N/A 沸点:N/A 熔点:N/A 闪点:N/A |