Synthesis, characterization, antidepressant and antioxidant activity of novel piperamides bearing piperidine and piperazine analogues

MK Prashanth, HD Revanasiddappa, KML Rai…

文献索引：Prashanth; Revanasiddappa, Hosakere D.; Lokanatha Rai; Veeresh Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 23 p. 7065 - 7070

全文：HTML全文

被引用次数: 21

摘要

A series of piperamide derivatives (8a–j) was synthesized with various substituted piperidine and piperazine compounds. The prepared compounds were evaluated for antibacterial activity against gram-positive and gram-negative bacteria and antifungal activity by disc diffusion method. The antioxidant activity of the compounds was evaluated by DPPH and superoxide radical scavenging method and antidepressant activity using forced swim and ...