Regio-and enantiocontrol in the room-temperature hydroboration of vinyl arenes with pinacol borane

CM Crudden, YB Hleba, AC Chen

文献索引：Crudden, Cathleen M.; Hleba, Yonek B.; Chen, Austin C. Journal of the American Chemical Society, 2004 , vol. 126, # 30 p. 9200 - 9201

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被引用次数: 136

摘要

The catalyzed hydroboration of vinyl arenes was carried out using pinacol borane instead of catechol borane, as the former reagent and the product boronates are significantly easier to handle. By careful choice of catalyst, either the branched or the linear product can be obtained in greater than 96% selectivity. Interestingly, common ligands such as BINAP and Josiphos give opposite asymmetric induction with pinacol borane as compared with ...