Organic Letters 2011-08-05

Ligand effects on Negishi couplings of alkenyl halides.

Arkady Krasovskiy, Bruce H Lipshutz

文献索引：Org. Lett. 13(15) , 3818-21, (2011)

全文：HTML全文

摘要

Negishi couplings at olefinic centers do not always occur with the anticipated maintenance of stereochemistry. The source of erosion has been traced to the ligand, and a modified method has been developed that solves the stereochemical issue and significantly improves yields of Negishi couplings in general.© 2011 American Chemical Society