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Synthetic Communications

Facile Synthesis of Isoquinolines, β??Carbolines, and 3??Deazapurines

W Huang, J Li, L Ou

文献索引:Huang, Wenhua; Li, Jingyi; Ou, Lihua Synthetic Communications, 2007 , vol. 37, # 13 p. 2137 - 2143

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被引用次数: 8

摘要

View all references to construct a tetrahydropyridine moiety followed by dehydrogenation. Natural β??aryl?螃窿?amino acid 1 can also undergo Pictet–Spengler cyclization to produce tetrahydropyridine derivative 2, whose oxidative decarboxylation can produce pyridine derivative 3 (Scheme 1). Such oxidative decarboxylation has been widely employed in synthesizing β??carbolines, but uses stoichiometric K 2 Cr 2 O 7 or toxic SeO 2 as an oxidant.66. Song , Y. , Wang , J. , ...