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Efficient and Practical One??Pot Conversions of N??Tosyltetrahydroisoquinolines into Isoquinolines and of N??Tosyltetrahydro?螃漫?carbolines into β??Carbolines through …

J Dong, XX Shi, JJ Yan, J Xing…

文献索引:Dong, Jing; Shi, Xiao-Xin; Yan, Jing-Jing; Xing, Jing; Zhang, Qiang; Xiao, Sen European Journal of Organic Chemistry, 2010 , # 36 p. 6987 - 6992

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被引用次数: 12

摘要

Abstract An efficient, practical, and general method for conversions of N- tosyltetrahydroisoquinolines (N-tosyl-THIQs) into isoquinolines and of N-tosyltetrahydro-β- carbolines (N-tosyl-THBCs) into β-carbolines is described. Treatment of N-tosyl-THIQs or N- tosyl-THBCs with base in dimethyl sulfoxide afforded dihydroisoquinolines or dihydro-β- carbolines as intermediates, and these were then oxidized in situ by molecular oxygen to ...