A Convenient Method for the Synthesis of 3, 5, 6-Trisubstituted-2-chloropyridines with bis-(Trichloromethyl) Carbonate

ZH Li, B Hong, WK Su

文献索引：Li; Hong; Su Organic Preparations and Procedures International, 2009 , vol. 41, # 6 p. 533 - 538

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被引用次数: 2

摘要

The pyridine ring system is found in a large number of naturally occurring alkaloids and synthetic products of biological interest. 1–4 Therefore, continuing studies forward the synthesis of pyridines are important in the field of drug design. As shown in Figure 1, 3, 5, 6- trisubstituted-2-chloropyridines have been extensively used as versatile building blocks for the synthesis of many heterocyclic systems with potential biological activity. 5, 6 The ...