Asymmetric synthesis of optically pure pharmacologically relevant amines employing ω??transaminases

D Koszelewski, I Lavandera, D Clay…

文献索引：Advanced Synthesis and Catalysis, , vol. 350, # 17 p. 2761 - 2766

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被引用次数: 126

摘要

... Keywords: amination; amines; asymmetric catalysis; biotransformations; transaminase ... Figure 2. Amination of 4-phenyl-2-butanone (1a) catalyzed by w-transaminase ATA ... In summary, enantioselective amination of prochiral ketones was demonstrated for the synthesis of phar- ...