Asymmetric synthesis of optically pure pharmacologically relevant amines employing ω??transaminases

D Koszelewski, I Lavandera, D Clay…

Index: Advanced Synthesis and Catalysis, , vol. 350, # 17 p. 2761 - 2766

Full Text: HTML

Citation Number: 126

Abstract

... Keywords: amination; amines; asymmetric catalysis; biotransformations; transaminase ... Figure 2. Amination of 4-phenyl-2-butanone (1a) catalyzed by w-transaminase ATA ... In summary, enantioselective amination of prochiral ketones was demonstrated for the synthesis of phar- ...