Discovery of potent nonpeptide inhibitors of stromelysin using SAR by NMR

PJ Hajduk, G Sheppard, DG Nettesheim…

文献索引：Journal of the American Chemical Society, , vol. 119, # 25 p. 5818 - 5827

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被引用次数: 346

摘要

... Journal of the ... 1997, 119 (25), pp 5818–5827. DOI: 10.1021/ja9702778. Publication Date (Web): June 25, 1997. Copyright © 1997 American Chemical Society. ... The compounds are screened by monitoring perturbations of the amide chemical shifts of 15 N-labeled protein upon the ...