Organic letters

Iron-catalyzed 2-arylbenzoxazole formation from o-nitrophenols and benzylic alcohols

M Wu, X Hu, J Liu, Y Liao, GJ Deng

文献索引：Wu, Mingyue; Hu, Xiong; Liu, Juan; Liao, Yunfeng; Deng, Guo-Jun Organic Letters, 2012 , vol. 14, # 11 p. 2722 - 2725

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被引用次数: 44

摘要

The iron-catalyzed 2-arylbenzoxazole formation from o-nitrophenols and benzylic alcohols using hydrogen transfer is described. Various 2-arylbenzoxazoles were selectively obtained in good to excellent yields. The reaction tolerated a wide range of functionalities. The alcohol oxidation, nitro reduction, condensation, and dehydrogenation were realized in a cascade without external reducing reagent and oxidant.