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Tetrahedron Letters

A green route for the synthesis of 2-substituted benzoxazole derivatives catalyzed by Al 3+-exchanged K10 clay

D Suresh, A Dhakshinamoorthy, K Pitchumani

文献索引:Suresh, Dhanusu; Dhakshinamoorthy, Amarajothi; Pitchumani, Kasi Tetrahedron Letters, 2013 , vol. 54, # 48 p. 6415 - 6419

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被引用次数: 9

摘要

Abstract A new, simple, and efficient protocol is developed for the synthesis of 2-substituted benzoxazole derivatives through N–C–O bond formation using Al 3+-exchanged K10 clay (Al 3+-K10) as catalyst. A wide range of benzoxazole derivatives are synthesized in high yields without affecting many functional groups. Hot filtration experiments showed the absence of metal leaching and catalyst can be reused for five times with only a slight ...