A new standardized electrochemical array for drug metabolic profiling with human cytochromes P450

…, E Capria, V Dodhia, P Panicco, S Collins…

文献索引：Fantuzzi, Andrea; Mak, Lok Hang; Capria, Ennio; Dodhia, Vikash; Panicco, Paola; Collins, Stephen; Gilardi, Gianfranco Analytical Chemistry, 2011 , vol. 83, # 10 p. 3831 - 3839

全文：HTML全文

被引用次数: 23

摘要

Over the past two decades, a wealth of information on the human cytochrome P450 enzymes and their role in drug metabolism both in vitro and in vivo has been gathered. Our understanding of this area has progressed greatly, but our confidence in the development of quantitative projections of drug interactions, made from in vitro data, is somehow still shaky. There are therefore no doubts in the necessity for reliable and fast methodologies for ...