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Journal of heterocyclic chemistry

Synthesis of 2??amino??4??imino??4, 5??dihydrothiazoles from N??sulfonyl?螃窿?chloroamidines and thiourea

SM Abdelaal, L Bauer

文献索引:Abdelaal, Salma; Bauer, Ludwig Journal of Heterocyclic Chemistry, 1988 , vol. 25, p. 1849 - 1856

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被引用次数: 2

摘要

Abstract A number of new and interesting 2-amino-4-(N-substituted) imino-4, 5- dihydrothiazoles were synthesized by reacting thiourea (or thiourea hydrochloride) with N- alkyl-or N, N-dialkyl-N′-p-toluenesulfonyl-α-chloroacetamidines, where the N, N-alkyl groups were ethyl, cyclohexyl, benzyl, β-phenethyl,(3, 5-dimethyl-1-adamantyl)-methyl, as well as N, N-dimethyl-and N, N-pentamethylene. Reactions of N-alkyl-Np-toluenesulfonyl- ...