Scandium Triflate as an Efficient and Recyclable Catalyst for the Deprotection of Tert??Butyl Aryl Sulfonamides

AK Mahalingam, X Wu, Y Wan…

文献索引：Mahalingam; Wu, Xiongyu; Wan, Yiqian; Alterman, Mathias Synthetic Communications, 2005 , vol. 35, # 3 p. 417 - 425

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被引用次数: 4

摘要

Abstract A mild and efficient method for deprotection of tert??butyl sulfonamide groups utilizing Sc (OTf) 3 as deprotecting reagent has been developed. A variety of tert??butyl aryl sulfonamides used under these conditions gave the corresponding primary sulfonamides in high yields. The Lewis acid catalyst could be fully recovered and reused with maintained activity after the reactions.