Organic Letters 2007-02-15

Ru-catalyzed intermolecular [3+2+1] cycloaddition of alpha,beta-unsaturated ketones with silylacetylenes and carbon monoxide leading to alpha-pyrones.

Takahide Fukuyama, Yuki Higashibeppu, Ryo Yamaura, Ilhyong Ryu

文献索引：Org. Lett. 9 , 587, (2007)

摘要

Ruthenium catalyzes a carbonylative [3+2+1] cycloaddition, using silylacetylenes, alpha,beta-unsaturated ketones, and CO as the starting materials, providing the new method for the synthesis of tetrasubstituted alpha-pyrones. In this reaction, the carbonyl group and alpha-carbon of vinyl ketones are incorporated as a three-atom assembling unit. [reaction: see text].

结构式	名称/CAS号	分子式	全部文献
	十二羰基三钌 CAS:15243-33-1	C₁₂O₁₂Ru₃

[Tetrahedron Lett. 22 , 1541, (1981)]

[J. Am. Chem. Soc. 106 , 4647, (1984)]

[J. Chem. Soc. Chem. Commun. , 1286, (1984)]

[J. Chem. Soc., Dalton Trans. , 2649, (1988)]

Ragaini, F. et al.
[Organometallics 18 , 928, (1999)]

Ru-catalyzed intermolecular [3+2+1] cycloaddition of alpha,beta-unsaturated ketones with silylacetylenes and carbon monoxide leading to alpha-pyrones.

摘要

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