Stereoselective oxazaborolidine–borane reduction of biphenyl alkyl diketones–lignin models: enantiopure dehydrodiapocynol derivatives

…, MA Dettori, A Patti, S Pedotti, A Forni, G Casalone

文献索引：Delogu, Giovanna; Dettori, Maria Antonietta; Patti, Angela; Pedotti, Sonia; Forni, Alessandra; Casalone, Gianluigi Tetrahedron Asymmetry, 2003 , vol. 14, # 16 p. 2467 - 2474

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被引用次数: 21

摘要

Asymmetric reduction of two conformationally flexible biphenyl alkyl diketones 9 and 10 with (R)-oxazaborolidine 3-borane system was successfully carried out and the corresponding biphenyl alcohols 11 and 12 were obtained in high yield and ee with predominance of the homochiral (S, S) dicarbinols. The absolute configuration of diastereopure dehydrodiapocynol derivative (S, S)-14 was assigned by crystallographic analysis which ...