Green chemistry

A simple and efficient protocol for a palladium-catalyzed ligand-free Suzuki reaction at room temperature in aqueous DMF

C Liu, Q Ni, F Bao, J Qiu

文献索引：Liu, Chun; Ni, Qijian; Bao, Fanying; Qiu, Jieshan Green Chemistry, 2011 , vol. 13, # 5 p. 1260 - 1266

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被引用次数: 82

摘要

A convenient, effective and mild protocol has been developed for the palladium-catalyzed ligand-free Suzuki reaction of aryl bromides with arylboronic acids in aqueous N, N- dimethylformamide (DMF) in the presence of K2CO3 and a catalytic amount of PdCl2 in air at room temperature. It is noteworthy that the volume ratio of water–DMF and base play important roles in the reaction, and various functional groups are tolerated under the ...