Copper (I)-Catalyzed Aryl Bromides To Form Intermolecular and Intramolecular Carbon− Oxygen Bonds

J Niu, P Guo, J Kang, Z Li, J Xu…

文献索引：Niu, Jiajia; Guo, Pengran; Kang, Juntao; Li, Zhigang; Xu, Jingwei; Hu, Shaojing Journal of Organic Chemistry, 2009 , vol. 74, # 14 p. 5075 - 5078

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被引用次数: 72

摘要

A highly efficient Cu-catalyzed C− O bond-forming reaction of alcohol and aryl bromides has been developed. This transformation was realized through the use of copper (I) iodide as a catalyst, 8-hydroxyquinoline as a ligand, and K3PO4 as a base. A variety of functionalized substrates were found to react under these reaction conditions to provide products in good to excellent yields.