Model fluorogenlc reagents have been synthesized and evaluated toward the goal of ultrahigh-sensltlvlty chromatographic analysls of prlmary amines with laser-based detection. Chemical reactlvlty and spectral crlterla were utilized to evaluate 12 potential reagents formlng hlghly fluorescent lsolndoles. 3-Benzoyl-2-quinollnecarboxaldehyde has been chosen at this tlme as the most promlslng reagent for the precolumn derlvatlzatlon of ...