Fluorescence reagents for high-sensitivity chromatographic measurements of primary amines

…, JC Savage, D Wiesler, SM Wietstock…

Index: Beale; Savage; Wiesler; Wietstock; Novotny Analytical Chemistry, 1988 , vol. 60, # 17 p. 1765 - 1769

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Citation Number: 57

Abstract

Model fluorogenlc reagents have been synthesized and evaluated toward the goal of ultrahigh-sensltlvlty chromatographic analysls of prlmary amines with laser-based detection. Chemical reactlvlty and spectral crlterla were utilized to evaluate 12 potential reagents formlng hlghly fluorescent lsolndoles. 3-Benzoyl-2-quinollnecarboxaldehyde has been chosen at this tlme as the most promlslng reagent for the precolumn derlvatlzatlon of ...