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Bulletin of the Chemical Society of Japan

An Easy Direct Conversion of Pyridine-and Pyrimidine-Thiones into Multi-Fused Heterocyclic Compounds.

AW Erian, FA Abu-Shanab

文献索引:Erian, Ayman Wahba; Abu-Shanab, Fathi Ali Bulletin of the Chemical Society of Japan, 1998 , vol. 71, # 10 p. 2387 - 2391

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被引用次数: 13

摘要

The reaction of azine-thiones with ethyl chlorofluoroacetate afforded 2-fluorothienoazines. The latter underwent self-condensation and gave multi-fused heterocyclic compounds. A wide range of unique heterocycles could be obtained on treatment of 2-fluorothienoazines with nitrogen nucleophilic reagents. The reactivity of the pyrimidine-thiones towards a variety of electrophilic reagents was studied. Chemical and spectroscopic evidence of the newly ...