Chinese Chemical Letters

Synthesis of novel uracil based 2, 5-diaminofurans using multi-component reactions

R Baharfar, SM Baghbanian

文献索引：Baharfar, Robabeh; Baghbanian, Seyed Meysam Chinese Chemical Letters, 2012 , vol. 23, # 6 p. 677 - 680

全文：HTML全文

被引用次数: 8

摘要

A simple synthesis of highly functionalized 2, 5-diaminofurans based pyrimidine derivatives from 1-(carboxymethyl) uracil via a multi-component reaction is described. The reactive 1: 1 intermediate produced from the reaction of tert-butyl isocyanide and dialkyl acetylenedicarboxylates was trapped at room temperature by 1-(carboxymethyl) uracil derivatives to yield polyfunctionalized furan rings in fairly good yields.