Synthesis of imidazolyl dithiocarbamates and their reactions with phenacyl bromides

OS El'tsov, VS Mokrushin, MV Smirnova…

文献索引：El'Tsov; Mokrushin; Smirnova; Shafikov Russian Chemical Bulletin, 2011 , vol. 60, # 5 p. 882 - 888

全文：HTML全文

被引用次数: 0

摘要

Abstract The reactions of ethyl (5-carbamoyl-3 H-imidazol-4-yl) dithiocarbamate with phenacyl bromides afford the S-alkylation products as a mixture of E/Z-isomers, which undergo cyclization to 5-(2-oxo-4-arylthiazol-3-yl)-1 H-imidazole-4-carboxamides under the action of a base.