Recueil des Travaux Chimiques des Pays??Bas Journal of the Royal Netherlands Chemical Society: General method for the synthesis of 3′, 5′??diesters and 2′?? …

JH van Boom, PMJ Burgers…

文献索引：Fache, Fabienne; Bethmont, Valerie; Jacquot, Laurent; Lemaire, Marc Recueil des Travaux Chimiques des Pays-Bas-Journal of the Royal Netherlands, 1996 , vol. 115, # 4 p. 231 - 238

全文：HTML全文

被引用次数: 0

摘要

Abstract A procedure suitable for the preparation on a large scale of 5′-O-(methoxyacetyl)- 3′-O-propionylribonucleosides (9a-d) from each of the four main ribonucleosides 6a-d has been developed. The usefulness of 9a-d as starting products for the synthesis of crystalline 2′-O-(methoxytetrahydropyranyl)-ribonucleosides (11a-d), which are key intermediates in the synthesis of oligoribonucleotides, has been demonstrated.