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Ring opening of aziridines by different fluorinating reagents: three synthetic routes to. alpha.,. beta.-fluoro amines with different stereochemical pathways

…, CM Ennakoua, SM Lacombe, AJ Laurent

文献索引:Alvernhe, Gerald M.; Ennakoua, Christine M.; Lacombe, Sylvie M.; Laurent, Andre J. Journal of Organic Chemistry, 1981 , vol. 46, # 24 p. 4938 - 4948

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被引用次数: 62

摘要

Results Two fluorinating agents were previously used with secondary aziridines (R= H), Le., anhydrous hydrogen fluoride and Olah's reagent. 16 Fluoro amines are generally obtained in fair yields (Table I). However, in some cases we could not get satisfactory results (ie, lOaT and lOaC,