Ring opening of aziridines by different fluorinating reagents: three synthetic routes to. alpha.,. beta.-fluoro amines with different stereochemical pathways

…, CM Ennakoua, SM Lacombe, AJ Laurent

Index: Alvernhe, Gerald M.; Ennakoua, Christine M.; Lacombe, Sylvie M.; Laurent, Andre J. Journal of Organic Chemistry, 1981 , vol. 46, # 24 p. 4938 - 4948

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Citation Number: 62

Abstract

Results Two fluorinating agents were previously used with secondary aziridines (R= H), Le., anhydrous hydrogen fluoride and Olah's reagent. 16 Fluoro amines are generally obtained in fair yields (Table I). However, in some cases we could not get satisfactory results (ie, lOaT and lOaC,