Versatile Synthesis of Acylfuranones by Reaction of Acylketenes with α??Hydroxy Ketones: Application to the One??Step Multicomponent Synthesis of Cadiolide B and …

PA Peixoto, A Boulangé, S Leleu…

文献索引：Peixoto, Philippe Alexandre; Boulange, Agathe; Leleu, Stephane; Franck, Xavier European Journal of Organic Chemistry, 2013 , # 16 p. 3316 - 3327

全文：HTML全文

被引用次数: 6

摘要

Abstract Functionalized acylfuranones have been prepared in a one-step procedure by thermal fragmentation of the corresponding dioxinones in the presence of hydroxy ketones in basic conditions. Multicomponent reactions also occur on addition of an aldehyde as a third reaction partner resulting in an expeditious access to cadiolide B and its analogues.

2632-13-5

4-甲氧基-α－溴代苯乙酮

~91%

4136-21-4

2-羟基-4'-甲氧基苯乙酮

~80%

~74%

~96%

~47%

A photochemical strategy for lignin degradation at room temp...

[Nguyen, John D.; Matsuura, Bryan S.; Stephenson, Corey R. J. Journal of the American Chemical Society, 2014 , vol. 136, # 4 p. 1218 - 1221]

Enzyme catalyzed hydroxymethylation of aromatic aldehydes wi...

[Demir, Ayhan S.; Ayhan, Peruze; Igdir, A. Cigdem; Duygu, A. Nese Tetrahedron, 2004 , vol. 60, # 31 p. 6509 - 6512]

Biocatalytic reduction of prochiral aromatic ketones to opti...

[Yan, Zhen; Nie, Yao; Xu, Yan; Liu, Xiang; Xiao, Rong Tetrahedron Letters, 2011 , vol. 52, # 9 p. 999 - 1002]

Additive Pummerer reactions of vinylic sulfoxides. Synthesis...

[Craig, Donald; Daniels, Kevin; MacKenzie, A. Roderick Tetrahedron, 1993 , vol. 49, # 48 p. 11263 - 11304]

Enzyme catalyzed hydroxymethylation of aromatic aldehydes wi...

[Demir, Ayhan S.; Ayhan, Peruze; Igdir, A. Cigdem; Duygu, A. Nese Tetrahedron, 2004 , vol. 60, # 31 p. 6509 - 6512]