Chemoselective addition of organotitanium reagents to carbonyl compounds

…, J Westermann, R Steinbach, B Wenderoth…

文献索引：Reetz, Manfred T.; Westermann, Juergen; Steinbach, Rainer; Wenderoth, Bernd; Peter, Roland; et al. Chemische Berichte, 1985 , vol. 118, # 4 p. 1421 - 1440

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被引用次数: 141

摘要

Abstract The conversion of classical carbanions such as RMgX, RLi, or deprotonated nitriles, sulfones, and carboxylic esters into titanium analogs results which add chemoselectively to carbonyl compounds in the presence of other functional groups. The standard titanating agent is chlorotrisopropoxytitanium (1). Grignard-type reactions and aldol additions are aldehyde-selective in the presence of ketones. Other functional groups such as alkyl and ...

~78%

~84%

~71%

~75%

~80%

~80%

~97%

~94%

~70%

~91%

~74%

~28%

~81%

~78%

~14%

~79%

~83%

~84%

~55%

~71%

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