Tetrahedron letters

Three-component condensations of aldehydes with N-methoxycarboxamides

CM Marson, S Pucci

文献索引：Marson, Charles M.; Pucci, Sabrina Tetrahedron Letters, 2004 , vol. 45, # 49 p. 9007 - 9010

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被引用次数: 10

摘要

The first condensations of N-methoxycarboxamides (component A) with aliphatic acetals (component B) are described. Depending upon the conditions, the hemiaminal type products (AB) can usually be isolated. Conducting the condensations with 2equiv of acetal affords β-(N-methoxy) amido aldehydes (type ABB products). A condensation using anisole (component C) afforded a product of type ABC.