Thermodynamics of phenylacetamides synthesis: Linear free energy relationship with the pK of amine

DT Guranda, GA Ushakov, PG Yolkin…

文献索引：Guranda, Dorel T.; Ushakov, Gennadij A.; Yolkin, Petr G.; Svedas, Vytas K. Journal of Molecular Catalysis B: Enzymatic, 2012 , vol. 74, # 1-2 p. 48 - 53

全文：HTML全文

被引用次数: 1

摘要

The effective equilibrium constants [Formula: see text] expressed through the total concentrations of the reagents for the synthesis of N-phenylacetyl-derivatives in aqueous medium from phenylacetic acid and various primary amino compounds have been determined with penicillin acylase as a catalyst. Broad specificity of penicillin acylase (EC 3.5. 1.11) to amino components made possible to investigate the acylation of primary ...