The synthesis of methyl benzylpenillonate

ABA Jansen, R Robinson

文献索引：Jansen,A.B.A.; Robinson,R. Monatshefte fuer Chemie, 1967 , vol. 98, # 3 p. 1017 - 1026

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被引用次数: 9

摘要

Abstract Methyl phenylpenicillenate (10) was formed by the interaction of 4-carbomethoxy-5, 5-dimethyl-Δ 2-thiazoline (6) and 2-phenyloxazol-5-one in pyridine, whereas in neutral solvents the preponderant product of the reaction was methyl phenylpenillonate (7). Similarly, under the latter conditions, 2-benzyloxazol-5-one (5) and the thiazoline (6) yield methyl benzylpenillonate (4, R= Ph· CH 2, R′= Me) identical with the product obtained ...