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Tetrahedron letters

Synthesis of diarylazepan-4-ones

MY Chang, YH Kung, CC Ma

文献索引:Chang, Meng-Yang; Kung, Yung-Hua; Ma, Chih-Chong Tetrahedron Letters, 2007 , vol. 48, # 2 p. 199 - 202

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被引用次数: 12

摘要

Synthesis of several 3, 3-diarylazepan-4-ones and 5, 5-diarylazepan-4-ones has been established starting from two tetrasubstituted olefins, which is derived from commercially available piperidine-3-carboxylic acid ethyl ester and piperidine-4-carboxylic acid ethyl ester. The single isomer with the structural skeleton of 3, 3-diarylazepan-4-one and 5, 5- diarylazepan-4-one is constructed in two functional group transformations of Grignard ...

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