Influence of polarity on the scalability and reproducibility of solvent-free microwave-assisted reactions
A Díaz-Ortiz, A de la Hoz, J Alcázar…
文献索引：Diaz-Ortiz, Ange; De La Hoz, Antonio; Alcazar, Jesus; Carrillo, Jose R.; Herrero, Maria A.; Fontana, Alberto; Munoz, Juan De M.; Prieto, Pilar; De Cozar, Abel Combinatorial Chemistry and High Throughput Screening, 2011 , vol. 14, # 2 p. 109 - 116
Organic reactions performed in the absence of solvent in domestic ovens without appropriate temperature control are generally considered as not reproducible, particularly when different instruments are used. For this reason, reproducibility has historically been one of the major issues associated with Microwave-Assisted Organic Synthesis (MAOS) especially when domestic ovens are involved. The lack of reproducibility limits the general ...
