One??pot synthesis of N2??aminoprotected 6??substituted and cycloalka [d] 4??trifluoromethyl??2??acetylaminopyrimidines

HG Bonacorso, A Ferla, CA Cechinel…

文献索引：Bonacorso, Helio G.; Ferla, Adriana; Cechinel, Cleber A.; Zanatta, Nilo; Martins, Marcos A. P. Journal of Heterocyclic Chemistry, 2008 , vol. 45, # 2 p. 483 - 487

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被引用次数: 13

摘要

Over the past 50 years numerous pyrimidines have been prepared and their pharmacology evaluated. Various 2-amino-4-substituted-5-alkylpyrimidines were reported to have diuretic activity and, in addition, numerous 2-aminopyrimidines have exhibited bacteriostatic, fungicidal and antiviral activity [1].