Synthesis

Practical large scale synthesis of tert-butyl (3R, 5S)-6-hydroxy-3, 5-O-isopropylidene-3, 5-dihydroxyhexanoate: essential building block for HMG-CoA reductase …

G Beck, H Jendralla, K Kesseler

文献索引：Synthesis, , # 8 p. 1014 - 1018

全文：HTML全文

被引用次数: 49

摘要

... 1994; revised 22 March 1995 Title compound 7 (96% ee, > 98% de) is synthesized enantiose- lectively in ... and we believe that it is currently the most practical method to synthesize homochiral HMG ... MS (DCI): m/Z (%) = 351 (M + H'", 9), 335 (M+ - CH3, 10), SYNTHESIS 1017 295 ...