Tetrahedron

Synthesis of 3-oxooxa-and 3-oxoazacycloalk-4-enes by ring-closing metathesis. Application to the synthesis of an inhibitor of cathepsin K

C Taillier, T Hameury, V Bellosta, J Cossy

文献索引：Taillier, Catherine; Hameury, Thomas; Bellosta, Veronique; Cossy, Janine Tetrahedron, 2007 , vol. 63, # 21 p. 4472 - 4490

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被引用次数: 37

摘要

Cyclic ethers and amines 1, 1a, 1b, 1c, 1d, 1e, 1f, 1g and 1h are present in a great variety of natural and non-natural products, which possess interesting biological properties. The interest for these heterocyclic compounds has stimulated the development of an array of methods for their synthesis. 2, 2a, 2b, 2c, 2d, 2e, 2f, 2g, 2h, 2i, 2j, 2k, 2l, 3, 3a, 3b, 3c, 3d and 3e The number of approaches available for the construction of cyclic ethers and amines has steadily ...